Exbio — Research products — Antibodies — CD and related antigens — Anti-Hu CD264 APC

Anti-Hu CD264 APC

Anti-Hu CD264 APC
Regulatory status
RUO
Antigen
CD264
Clone
TRAIL-R4-01
Format
APC
Reactivity
Human
Application
FC (QC tested)
Excitation laser
red (633 nm)
Variant
0.1 mg
1A-519-C100
Out of stock
0.00 USD
Variant
0.1 mg
11-261-C100
In stock
0.00 USD
Contact distributor
Product details
Images
References
Isotype
Mouse IgG1
Specificity
The antibody TRAIL-R4-01 reacts with an extracellular epitope of TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.
Application
FC (QC tested)
Reactivity
Human
Immunogen
TRAIL-R4 (aa 1-210) - hIgGhc fusion protein
Other names
TNFRSF10D, DcR2, TRUNDD, TRAILR4
Concentration
0.1 mg/ml
Preparation
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
1A-519_FC_Profil Značení
Flow cytometry surface staining pattern of CD264 transfected HEK-293 cells using anti-human CD264 (TRAIL-R4-01) APC (concentration in sample 1,67 μg/ml).
1A-519_FC_Histogram
Separation of cells stained using anti-human CD264 (TRAIL-R4-01) APC antibody (concentration in sample 1,67 μg/ml, red-filled) from CD264 cells stained using mouse IgG1 isotype control (MOPC-21) APC antibody (concentration in sample 1,67 μg/ml, black-dashed) in flow cytometry analysis (surface staining) of CD264 transfected HEK-293 cell suspension.

General references:

Deligezer U, Dalay N: Expression of the TRAIL Receptors in Blood Mononuclear Cells in Leukemia. Pathol Oncol Res. 2007;13(4):290-4.
PubMed
Falschlehner C, Emmerich CH, Gerlach B, Walczak H: TRAIL signalling: decisions between life and death. Int J Biochem Cell Biol. 2007;39(7-8):1462-75.
PubMed
Mérino D, Lalaoui N, Morizot A, Schneider P, Solary E, Micheau O: Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol. 2006 Oct;26(19):7046-55.
PubMed
Sanlioglu AD, Dirice E, Aydin C, Erin N, Koksoy S, Sanlioglu S. Surface TRAIL decoy receptor-4 expression is correlated with TRAIL resistance in MCF7 breast cancer cells. BMC Cancer. 2005 May 25;5(1):54.
PubMed
Clancy L, Mruk K, Archer K, Woelfel M, Mongkolsapaya J, Screaton G, Lenardo MJ, Chan FK: Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18099-104.
PubMed
Variant
0.1 mg
1A-519-C100
Out of stock
0.00 USD
Variant
0.1 mg
11-261-C100
In stock
0.00 USD
Contact distributor
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