Anti-Hu CD245 Purified

Anti-Hu CD245 Purified
Regulatory status
RUO
Antigen
CD245
Clone
DY12
Format
Purified
Reactivity
Human
Variant
0.1 mg
11-941-C100
In stock
154.00 USD
Variant
0.1 mg
11-941-C100
In stock
154.00 USD
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG1 kappa
Specificity
The mouse monoclonal antibody DY12 recognizes an extracellular epitope of CD245, a transmembrane protein expressed mainly by peripheral blood lymphocytes, NK cells, monocytes, granulocytes and platelets.
Workshop
HLDA VI, HLDA VII
Application details
Flow cytometry: Recommended dilution: 1-5 μg/ml.
Reactivity
Human
Immunogen
human NK-type YT2C2 cells
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
p220/240, DY12, DY35
Antigen description
CD245 is a 220-250 kDa transmembrane protein of unknown structure. It is expressed at lower level on resting blood lymphocytes, granulocytes, platelets, and thymocytes, and at high level on monocytes and on IL-2-dependent T cell lines. It is also expressed on Ewing sarcoma and osteosarcoma cell lines. CD245 seems to act as a costimulation molecule of T and NK cells.
11-941_FC_Profil Značení
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD245 (DY12) purified antibody (concentration in sample 1.67 μg/ml, GAM APC).
11-941_FC_Histogram
Separation of monocytes (red-filled) stained using anti-human CD245 (DY12) purified antibody (concentration in sample 1.67 μg/ml, GAM APC) from monocytes cells unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood.

Product specific references:

Kishimoto et al.: Leucocyte typing VI, Garland Publishing 1996
Mason et al.: Leucocyte typing VII, Oxford University Press 2000
Variant
0.1 mg
11-941-C100
In stock
154.00 USD
Variant
0.1 mg
11-941-C100
In stock
154.00 USD

Related products

-134%
Reg. statusCE IVD
ApplicationFC
100 ml
220.00 USD
-134%
Reg. statusCE IVD
ApplicationFC
100 ml
66.00 USD
-134%
Reg. statusRUO
ApplicationFC
100 ml
55.00 USD
-134%
CloneMOPC-21
Reg. statusRUO
0.1 mg
115.50 USD