Anti-Hu CD2 Biotin

Anti-Hu CD2 Biotin
Regulatory status
RUO
Antigen
CD2
Clone
MEM-65
Format
Biotin
Reactivity
Human
Application
IP, FC (QC tested)
Variant
0.1 mg
1B-201-C100
In stock

0.025 mg
1B-201-C025
Out of stock
Variant
0.1 mg
11-261-C100
In stock

0.1 mg
11-261-C100
In stock
Product details
Images
References
Isotype
Mouse IgG1
Specificity
The antibody MEM-65 recognizes an unique epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T-lymphocytes and NK cells; also expressed by all thymocytes.
Workshop
HLDA VI: WS Code T 6T-012
Application
IP, FC (QC tested)
Reactivity
Human
Immunogen
Human peripheral T cells.
Other names
T11, LFA-2, SRBC
Concentration
1 mg/ml
Preparation
The purified antibody is conjugated with biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Exbio licence note
Unless indicated otherwise, all products are For Research Use Only and not for diagnostic use. In vivo diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s. © 2019 EXBIO Praha, a.s. All rights reserved.
1B-201 FC
Flow cytometry analysis (surface staining) of human peripheral blood with anti-human CD2 (MEM-65) biotin, streptavidin-APC.

General references:

Pawlowski NN, Struck D, Grollich K, Kuhl AA, Zeitz M, Liesenfeld O, Hoffmann JC: CD2 deficiency partially prevents small bowel inflammation and improves parasite control in murine Toxoplasma gondii infection. World J Gastroenterol. 2007 Aug 21;13(31):4207-13.
PubMed
Zhu DM, Dustin ML, Cairo CW, Thatte HS, Golan DE: Mechanisms of Cellular Avidity Regulation in CD2-CD58-Mediated T Cell Adhesion. ACS Chem Biol. 2006 Nov 21;1(10):649-58.
PubMed
Dustin ML: Adhesive bond dynamics in contacts between T lymphocytes and glass-supported planar bilayers reconstituted with the immunoglobulin-related adhesion molecule CD58. J Biol Chem. 1997 Jun 20;272(25):15782-8.
PubMed
Pawlowski NN, Struck D, Grollich K, Kuhl AA, Zeitz M, Liesenfeld O, Hoffmann JC: CD2 deficiency partially prevents small bowel inflammation and improves parasite control in murine Toxoplasma gondii infection. World J Gastroenterol. 2007 Aug 21;13(31):4207-13.
PubMed

Product specific references:

Drbal K, Hilgert I, Cebecauer M, Angelisova P, Horejsi V: New monoclonal antibodies to human leucocyte surface molecule CD2. Folia Biol (Praha). 1997;43(6):245-6.
PubMed
Espagnolle N, Depoil D, Zaru R, Demeur C, Champagne E, Guiraud M, Valitutti S: CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse. Int Immunol. 2007 Mar;19(3):239-48.
PubMed
Ilangumaran S, Briol A, Hoessli DC: CD44 selectively associates with active Src family protein tyrosine kinases Lck and Fyn in glycosphingolipid-rich plasma membrane domains of human peripheral blood lymphocytes. Blood. 1998 May 15;91(10):3901-8.
PubMed
Drbal K, Hilgert I, Cebecauer M, Angelisova P, Horejsi V: New monoclonal antibodies to human leucocyte surface molecule CD2. Folia Biol (Praha). 1997;43(6):245-6.
PubMed
Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).
Variant
0.1 mg
1B-201-C100
In stock

0.025 mg
1B-201-C025
Out of stock
Variant
0.1 mg
11-261-C100
In stock

0.1 mg
11-261-C100
In stock