Exbio — Research products — Antibodies — CD and related antigens — Anti-Hu CD187 Purified

Anti-Hu CD187 Purified

Regulatory status

RUO

Antigen

CD187

Clone

10D1-J16

Format

Purified

Reactivity

Human

Application

FC (QC tested)

Variant

0.1 mg

11-879-C100

Ask for delivery term HERE

158.40 USD

Variant

0.1 mg

11-879-C100

Ask for delivery term HERE

158.40 USD

Contact distributor

Product details

Description

Images

References

SDS download

Isotype

Mouse IgG2a kappa

Specificity

The mouse monoclonal antibody 10D1-J16 recognizes an extracellular epitope on CD187/CXCR7, a transmembrane protein of chemokine receptor family.

Application

FC (QC tested)

Application details

Flow cytometry: Recommended dilution: 1-12 µg/ml

Reactivity

Human

Concentration

1 mg/ml

Preparation

Purified by protein-A affinity chromatography.

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

CXCR7, RDC1, GPR159, ACKR3

Antigen description

CD187 (CXCR7) is a member of chemokine receptor family, but with discussed specificity. It is expressed in various tissues and cells, such as placenta, urinary bladder, fetal liver cells, tumor cells, activated endothelium, monocytes, lymphocytes, mature dendritic cells, and other.

Entrez Gene ID 57007

UniProt ID P25106

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD187 (10D1-J16) purified antibody (concentration in sample 1,7 μg/ml, GAM APC).

Separation of monocytes stained anti-human CD187 (10D1-J16) purified antibody (concentration in sample 1,7 μg/ml, GAM APC, red-filled) from monocytes unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).

Product specific references:

Doijen J, Van Loy T, De Haes W, Landuyt B, Luyten W, Schoofs L, Schols D: Signaling properties of the human chemokine receptors CXCR4 and CXCR7 by cellular electric impedance measurements. PLoS One. 2017 Sep 25;12(9):e0185354.
PubMed

Espinoza-Sánchez NA, Vadillo E, Balandrán JC, Monroy-García A, Pelayo R, Fuentes-Pananá EM: Evidence of lateral transmission of aggressive features between different types of breast cancer cells. Int J Oncol. 2017 Nov;51(5):1482-1496.
PubMed

Guan L, Li X, Wei J, Liang Z, Yang J, Weng X, Wu X: Antigen-specific CD8+ memory stem T cells generated from human peripheral blood effectively eradicate allogeneic targets in mice. Stem Cell Res Ther. 2018 Dec 7;9(1):337.
PubMed