Exbio — Research products — Antibodies — CD and related antigens — Anti-Hu CD183 Purified

Anti-Hu CD183 Purified

Regulatory status

RUO

Antigen

CD183

Clone

rHIQB005

Format

Purified

Reactivity

Human

Application

FC (QC tested)

Variant

0.1 mg

11-960-C100

In stock

158.40 USD

Variant

0.1 mg

11-960-C100

In stock

158.40 USD

Contact distributor

Product details

Description

Images

SDS download

Isotype

Mouse IgG1

Specificity

The recombinant mouse monoclonal antibody rHIQB005 recognizes an extracellular epitope on human chemokine receptor CD184.

Application

FC (QC tested)

Application details

Flow cytometry: Recommended dilution: 1-5 μg/ml

Reactivity

Human

Description

Recombinant monoclonal antibody is expressed in CHO cell culture.

Concentration

1 mg/ml

Preparation

Purified by affinity chromatography.

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

CXCR3, fusin, CKR-L2, CMKAR3, GPR9, IP10-R, MIG-R

Antigen description

CD184 is a 7-transmembrane G-protein coupled receptor for the C-X-C chemokines SDF-1 (CXCL12), MIG (CXCL9) and IP10 (CXCL10). Alternatively spliced variant CD184B serves as the high affinity receptor for PF4 (CXCL4). CD184 is expressed in hematopoietic cells, vascular endothelium, and neural tissue. It plays important roles in endothelial vascularization and central nervous system development. It can also serve as a primary receptor or a coreceptor for some HIV isolates. CD184 signaling leads to integrin activation, cytoskeletal changes and chemotactic migration.

Entrez Gene ID 2833

UniProt ID P49682

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD183 (rHIQB005) purified antibody (concentration in sample 5 μg/ml, GAM APC).

Separation of human CD183 positive lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD183 (rHIQB005) purified antibody (concentration in sample 5 μg/ml, GAM APC).