Anti-Hu CD172g PE

Anti-Hu CD172g PE
Regulatory status
RUO
Antigen
CD172g
Clone
OX-119
Format
PE
Reactivity
Human
Excitation laser
blue (488 nm)
Variant
100 tests
1P-881-T100
In stock
220.00 USD
Variant
0.1 mg
11-261-C100
In stock
220.00 USD
Product details
Description
Images
References
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody OX-119 recognizes an extracellular epitope on CD172g, an approximately 55 kDa transmembrane glycoprotein expressed on most T cells, as well as on NK cells and some B cell populations.
Application details
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity
Human
Immunogen
recombinant human CD172g
Preparation
The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
SIRP gamma, SIRP-B2
Antigen description
CD172g is a transmembrane glycoprotein, which may play a role in inter-T cellular signaling by binding CD47, and thus in influencing T cell behaviour. CD172g is expressed on mature thymocytes, CD4+ T cells, CD8+ T cells, NK cells, and some B cells. It is absent on myeloid cells. Engagement of CD172g by CD47 expressed on antigen presenting cells results in enhanced antigen-specific T cell proliferation and costimulates T cell activation.
Entrez Gene ID 55423
UniProt ID Q9P1W8
1P-881_FC_profil značení
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD172g (OX-119) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).
1P-881_FC_Histogram
Separation of human CD172g positive lymphocytes (red-filled) from CD172g negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD172g (OX-119) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).

Product specific references:

Nettleship JE, Ren J, Rahman N, Berrow NS, Hatherley D, Barclay AN, Owens RJ: A pipeline for the production of antibody fragments for structural studies using transient expression in HEK 293T cells. Protein Expr Purif. 2008 Nov;62(1):83-9
PubMed
Brooke G, Holbrook JD, Brown MH, Barclay AN: Human lymphocytes interact directly with CD47 through a novel member of the signal regulatory protein (SIRP) family. J Immunol. 2004 Aug 15;173(4):2562-70
PubMed
Variant
100 tests
1P-881-T100
In stock
220.00 USD
Variant
0.1 mg
11-261-C100
In stock
220.00 USD