Anti-Hu CD158z PE

Anti-Hu CD158z PE
Regulatory status
RUO
Antigen
CD158z
Clone
CH21
Format
PE
Reactivity
Human
Application
Excitation laser
blue (488 nm)
Variant
0.1 mg
1P-945-C100
In stock
242.00 USD
Variant
0.1 mg
1P-945-C100
In stock
242.00 USD
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG2a
Specificity
The mouse monoclonal antibody CH21 recognizes an extracellular epitope of human CD158z (KIR3DL3), a transmembrane glycoprotein of killer cell inhibitory receptor family.
Application
Application details
Flow cytometry: Recommended dilution: 1-5 µg/ml
Reactivity
Human
Immunogen
human CD158z transfectants
Concentration
0.1 mg/ml
Preparation
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
KIR3DL3
Antigen description
CD158z (KIR3DL3)is one of killer cell inhibitory receptors. It has three extracellular immunoglobulin-like domains and a long cytoplasmic tail, which, however, contains only one ITIM. Like other KIRs, CD158z is highly polymorphic, but it seems that its immunoglobulin-like domains are quite conserved among high primates.
Entrez Gene ID 115653
UniProt ID Q8N743
1P-945_FC_Histogram
Separation of CD158z positive cells (red-filled) from CD158z negative cells (black-dashed) in flow cytometry analysis (surface staining) of KIR3DL3 (CD158z) transfected HEK-293 suspension stained using anti-human CD158z (CH21) PE antibody (concentration in sample 5 μg/ml).
1P-945_FC_Profil Značení
Flow cytometry surface staining patterns of KIR3DL3 (CD158z) transfected HEK-293 suspension stained using anti-human CD158z (CH21) PE antibody (concentration in sample 5 μg/ml, left) or mouse IgG2a isotype control (MOPC-173) PE antibody (concentration in sample 5 μg/ml, same as CD158z PE concentration, right).

Product specific references:

Trundley AE, Hiby SE, Chang C, Sharkey AM, Santourlidis S, Uhrberg M, Trowsdale J, Moffett A: Molecular characterization of KIR3DL3. Immunogenetics 2006 Jan;57(12):904-16.
PubMed
Variant
0.1 mg
1P-945-C100
In stock
242.00 USD
Variant
0.1 mg
1P-945-C100
In stock
242.00 USD

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