Anti-Hu CD158z APC

Anti-Hu CD158z APC
Regulatory status
RUO
Antigen
CD158z
Clone
CH21
Format
APC
Reactivity
Human
Application
Excitation laser
red (633 nm)
Variant
0.1 mg
1A-945-C100
Ask for delivery term HERE
242.00 USD
Variant
0.1 mg
1A-945-C100
Ask for delivery term HERE
242.00 USD
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG2a
Specificity
The mouse monoclonal antibody CH21 recognizes an extracellular epitope of human CD158z (KIR3DL3), a transmembrane glycoprotein of killer cell inhibitory receptor family.
Application
Application details
Flow cytometry: Recommended dilution: 3-12 µg/ml
Reactivity
Human
Immunogen
human CD158z transfectants
Concentration
0.1 mg/ml
Preparation
Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
KIR3DL3
Antigen description
CD158z (KIR3DL3)is one of killer cell inhibitory receptors. It has three extracellular immunoglobulin-like domains and a long cytoplasmic tail, which, however, contains only one ITIM. Like other KIRs, CD158z is highly polymorphic, but it seems that its immunoglobulin-like domains are quite conserved among high primates.
Entrez Gene ID 115653
UniProt ID Q8N743
1A-945_FC_Dot-plot
Flow cytometry surface staining pattern of KIR3DL3 (CD158z) transfected HEK-293 cells co-transfected with YFP coding plasmid using anti-human CD158z (CH21) APC antibody (concentration in sample 10 μg/ml).
1A-945_FC_Dot-plot_2
Flow cytometry surface staining patterns of non-transfected HEK-293 cells and HEK-293 cells transfected with KIR-family coding plasmids co-transfected with YFP coding plasmid using anti-human CD158z (CH21) APC antibody (concentration in sample 10 μg/ml).

Product specific references:

Trundley AE, Hiby SE, Chang C, Sharkey AM, Santourlidis S, Uhrberg M, Trowsdale J, Moffett A: Molecular characterization of KIR3DL3. Immunogenetics 2006 Jan;57(12):904-16.
PubMed
Variant
0.1 mg
1A-945-C100
Ask for delivery term HERE
242.00 USD
Variant
0.1 mg
1A-945-C100
Ask for delivery term HERE
242.00 USD

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