Exbio — Research products — Antibodies — CD and related antigens — Anti-Hu CD151 Purified

Anti-Hu CD151 Purified

Regulatory status

RUO

Antigen

CD151

Clone

50-6

Format

Purified

Reactivity

Human

Application

WB, FC (QC tested), IHC(F), ICC

Variant

0.1 mg

11-149-C100

In stock

143.00 USD

0.025 mg

11-149-C025

Delivery 1 week

71.50 USD

Variant

0.1 mg

11-149-C100

In stock

143.00 USD

0.025 mg

11-149-C025

Delivery 1 week

71.50 USD

Contact distributor

Product details

Description

Images

References

SDS download

Isotype

Mouse IgG1 kappa

Specificity

The mouse monoclonal antibody CD151 recognizes an extracellular epitope of CD151 (also known as PETA-3), a 29 kDa transmembrane protein of tetraspanin family, expressed in many cell types.

Application

WB, FC (QC tested), IHC(F), ICC

Application details

Flow cytometry: Recommended dilution: 2-4 μg/ml.

Reactivity

Human

Immunogen

Human epidermoid carcinoma cell line Hep-3

Concentration

1 mg/ml

Preparation

Purified by protein-A affinity chromatography.

Formulation

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage and handling

Store at 2-8°C. Do not freeze.

The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Other names

RAPH blood group, MER2, SFA1, PETA-3, GP27

Antigen description

CD151, also known as PETA-3 (platelet-endothelial tetraspan antigen), is a four-pass transmembrane glycoprotein with short cytoplasmic N- and C-termini. CD151 is expressed mainly in platelets and megakaryocytes, immature hematopoietic cells, activated T cells, in endothelium, muscle cells, and epithelial cells. It associates with CD9, CD181, and integrin complexes alpha 3 / beta 1 (CD49c / CD29), alpha 5 / beta 1 (CD49e / CD29), and alpha 6 / beta 4 (CD49f / CD104). CD151 appears to be involved in cell adhesion and migration, including metastasis.

Entrez Gene ID 977

UniProt ID P48509

Flow cytometry analysis (surface staining) of human peripheral blood with anti-human CD151 (50-6) PE.

Product specific references:

Sadej R, Grudowska A, Turczyk L, Kordek R, Romanska HM: CD151 in cancer progression and metastasis: a complex scenario. Lab Invest. 2014 Jan;94(1):41-51.
PubMed

Spring FA, Griffiths RE, Mankelow TJ, Agnew C, Parsons SF, Chasis JA, Anstee DJ: Tetraspanins CD81 and CD82 facilitate α4β1-mediated adhesion of human erythroblasts to vascular cell adhesion molecule-1. PLoS One. 2013 May 21;8(5):e62654.
PubMed