Anti-Hu CD143 Purified

Anti-Hu CD143 Purified
Regulatory status
RUO
Antigen
CD143
Clone
5-369
Format
Purified
Reactivity
Human
Application
FC (QC tested)
Variant
0.1 mg
11-796-C100
In stock
130.00 USD

0.025 mg
11-796-C025
Ask for delivery term HERE
65.00 USD
Variant
0.1 mg
11-261-C100
In stock
130.00 USD

0.1 mg
11-261-C100
In stock
65.00 USD
Product details
Description
Images
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody 5-369 recognizes an extracellular epitope of CD143, a 171 kDa type I transmembrane glycoprotein with metallopeptidase activity, expressed mainly on endothelial cells.
Application
FC (QC tested)
Application details
Flow cytometry: Recommended dilution: 1-4 µg/ml
Reactivity
Human
Immunogen
dendritic cells
Other names
DCP, ACE1, DCP1, carboxycathepsin, kininase II, peptidase P, peptidyl dipeptidase 1
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
DCP, ACE1, DCP1, carboxycathepsin, kininase II, peptidase P, peptidyl dipeptidase 1
Antigen description
CD143, also known as ACE (angiotensin-converting enzyme), carboxycathepsin, kininase II, peptidase P, or peptidyl dipeptidase 1, is a transmembrane zinc metallopeptidase catalyzing the conversion of angiotensin I into the physiologically active angiotensin II, which is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, that are equally active. CD143 is expressed mainly on endothelial cells, but it can be found also e.g. on activated macrophages and histiocytes.
Entrez Gene ID 1636
UniProt ID P12821
11-796_FC_Profil Značení
Flow cytometry surface staining pattern of human GM-CSF + IL-4 stimulated peripheral blood mononuclear cells stained using anti-human CD143 (5-369) purified antibody (concentration in sample 0,6 μg/ml) GAM APC.
11-796_FC_Histogram
Separation of human stimulated monocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human GM-CSF + IL-4 stimulated peripheral blood mononuclear cells stained using anti-human CD143 (5-369) purified antibody (concentration in sample 0,6 μg/ml) GAM APC.
Variant
0.1 mg
11-796-C100
In stock
130.00 USD

0.025 mg
11-796-C025
Ask for delivery term HERE
65.00 USD
Variant
0.1 mg
11-261-C100
In stock
130.00 USD

0.1 mg
11-261-C100
In stock
65.00 USD