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Exbio
—
Research products
—
Antibodies
—
CD and related antigens
—
Anti-Hu CD143 Purified
Anti-Hu CD143 Purified
Regulatory status
RUO
Antigen
CD143
Clone
5-369
Format
Purified
Reactivity
Human
Application
FC (QC tested)
Variant
0.1 mg
11-796-C100
In stock
143.00 USD
0.025 mg
11-796-C025
Delivery 1 week
71.50 USD
Variant
0.1 mg
11-796-C100
In stock
143.00 USD
0.025 mg
11-796-C025
Delivery 1 week
71.50 USD
Contact distributor
Product details
Description
Images
SDS download
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody 5-369 recognizes an extracellular epitope of CD143, a 171 kDa type I transmembrane glycoprotein with metallopeptidase activity, expressed mainly on endothelial cells.
Application
FC (QC tested)
Application details
Flow cytometry: Recommended dilution: 1-4 µg/ml
Reactivity
Human
Immunogen
dendritic cells
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
DCP, ACE1, DCP1, carboxycathepsin, kininase II, peptidase P, peptidyl dipeptidase 1
Antigen description
CD143, also known as ACE (angiotensin-converting enzyme), carboxycathepsin, kininase II, peptidase P, or peptidyl dipeptidase 1, is a transmembrane zinc metallopeptidase catalyzing the conversion of angiotensin I into the physiologically active angiotensin II, which is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, that are equally active. CD143 is expressed mainly on endothelial cells, but it can be found also e.g. on activated macrophages and histiocytes.
Entrez Gene ID
1636
UniProt ID
P12821
Flow cytometry surface staining pattern of human GM-CSF + IL-4 stimulated peripheral blood mononuclear cells stained using anti-human CD143 (5-369) purified antibody (concentration in sample 0,6 μg/ml) GAM APC.
Separation of human stimulated monocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human GM-CSF + IL-4 stimulated peripheral blood mononuclear cells stained using anti-human CD143 (5-369) purified antibody (concentration in sample 0,6 μg/ml) GAM APC.
Further SDS language mutations available for download below. Please contact us with request for additional languages on info@exbio.cz
MPAbNaN3_SDS_v1_AU.pdf
MPAbNaN3_SDS_v1_GB.pdf
MPAbNaN3_SDS_v1_TR.pdf
MPAbNaN3_SDS_v6_AT.pdf
MPAbNaN3_SDS_v6_CH.pdf
MPAbNaN3_SDS_v6_CS.pdf
MPAbNaN3_SDS_v6_EN.pdf
MPAbNaN3_SDS_v6_ES.pdf
MPAbNaN3_SDS_v6_FR.pdf
MPAbNaN3_SDS_v6_IT.pdf
MPAbNaN3_SDS_v6_NO.pdf
MPAbNaN3_SDS_v6_PL.pdf
MPAbNaN3_SDS_v6_PT.pdf
MPAbNaN3_SDS_v6_SE.pdf
MPAbNaN3_SDS_v6_SK.pdf
MPAbNaN3_SDS_v6_SL.pdf
MPAbNaN3_SDS_v7_DE.pdf
Variant
0.1 mg
11-796-C100
In stock
143.00 USD
0.025 mg
11-796-C025
Delivery 1 week
71.50 USD
Variant
0.1 mg
11-796-C100
In stock
143.00 USD
0.025 mg
11-796-C025
Delivery 1 week
71.50 USD
Contact distributor
Datasheet download
Bulk requests
Technical support for this product
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