Anti-Hu CD132 Purified

Anti-Hu CD132 Purified
Regulatory status
RUO
Antigen
CD132
Clone
TUGh4
Format
Purified
Reactivity
Human, Dog
Application
FC (QC tested)
Variant
0.1 mg
11-194-C100
In stock
Variant
0.1 mg
11-261-C100
In stock
Product details
References
Isotype
Rat IgG2b kappa
Specificity
The rat monoclonal antibody TUGh4 recognizes CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.
Workshop
HLDA VI: WS Code C-89
Application
FC (QC tested)
Reactivity
Human, Dog
Immunogen
Human CD132-transfected cell line
Other names
common gamma chain, interleukin 2 receptor gamma, IL2RG, SCIDX, IMD4
Preparation
Purified from cell culture supernatant by protein-G affinity chromatography
Formulation
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Exbio licence note
Unless indicated otherwise, all products are For Research Use Only and not for diagnostic use. In vivo diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s. © 2019 EXBIO Praha, a.s. All rights reserved.

Product specific references:

Corrigall VM, Arastu M, Khan S, Shah C, Fife M, Smeets T, Tak PP, Panayi GS: Functional IL-2 receptor beta (CD122) and gamma (CD132) chains are expressed by fibroblast-like synoviocytes: activation by IL-2 stimulates monocyte chemoattractant protein-1 production. J Immunol. 2001 Mar 15;166(6):4141-7.
PubMed
Brisslert M, Bokarewa M, Larsson P, Wing K, Collins LV, Tarkowski A: Phenotypic and functional characterization of human CD25+ B cells. Immunology. 2006 Apr;117(4):548-57.
PubMed
Amu S, Brisslert M: Phenotype and function of CD25-expressing B lymphocytes isolated from human umbilical cord blood. Clin Dev Immunol. 2011;2011:481948.
PubMed
Fiorito S, Magrini L, Adrey J, Mailhé D, Brouty-Boyé D: Inflammatory status and cartilage regenerative potential of synovial fibroblasts from patients with osteoarthritis and chondropathy. Rheumatology (Oxford). 2005 Feb;44(2):164-71.
PubMed
Marino JH, Tan C, Taylor AA, Bentley C, Van De Wiele CJ, Ranne R, Paliotta M, Broughan TA, Teague TK: Differential IL-7 responses in developing human thymocytes. Hum Immunol. 2010 Apr;71(4):329-33.
PubMed
Itano M, Tsuchiya S, Morita S, Fujie H, Ishii N, Yanagisawa T, Ohashi Y, Minegishi M, Sugamura K, Konno T: IL-2 receptor gamma chain expression on CD34 positive hematopoietic progenitor cells from bone marrow and cord blood. Tohoku J Exp Med. 1996 Apr;178(4):389-98.
PubMed
Variant
0.1 mg
11-194-C100
In stock
Variant
0.1 mg
11-261-C100
In stock