Anti-Hu CD101 Purified

Anti-Hu CD101 Purified
Regulatory status
RUO
Antigen
CD101
Clone
BB27
Format
Purified
Reactivity
Human
Variant
0.1 mg
11-778-C100
In stock
143.00 USD

0.025 mg
11-778-C025
Delivery 1 week
71.50 USD
Variant
0.1 mg
11-778-C100
In stock
143.00 USD

0.025 mg
11-778-C025
Delivery 1 week
71.50 USD
Product details
Description
Images
References
SDS download
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody BB27 recognizes an extracellular epitope of CD101, a 140 kDa disulfide-bonded homodimeric protein expressed on activated T cells, and some other cell types, such as granulocytes and cells of the monocyte/macropgage lineage.
Workshop
HLDA V: WS Code T040
Application details
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Reactivity
Human
Immunogen
Human thymic clone B12
Concentration
1 mg/ml
Preparation
Purified by protein-A affinity chromatography.
Formulation
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage and handling
Store at 2-8°C. Do not freeze.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Other names
IGSF2, V7, EWI-101
Antigen description
CD101 is a type I transmembrane glycoprotein, which forms disulfide-linked homodimers. It is expressed on activated T cells, as well as on granulocytes, monocytes, dendritic cells or mucosal T cells. It plays a major role in the activation of T cells by skin dendritic cells. Function of CD101 has not been fully elucidated, but in mice its knock-out results in liver autoimmune disease induced by Novosphingobium aromaticivorans.
Entrez Gene ID 9398
UniProt ID Q93033
11-778_FC_Profil Značení
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD101 (BB27) purified antibody (concentration in sample 0,56 μg/ml, GAM FITC).
11-778_FC_Dot-plot
Flow cytometry multicolor surface staining of human lymphocytes stained using anti-human CD101 (BB27) purified antibody (concentration in sample 0,56 μg/ml, GAM FITC) and anti-human CD16 (3G8) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
11-778_FC_Histogram
Separation of human CD101 positive CD16 negative lymphocytes (red-filled) CD101 negative CD16 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood using anti-human CD101 (BB27) purified antibody (concentration in sample 0,56 μg/ml, GAM FITC).

Product specific references:

Bagot M, Martinel I, Charue D, Boulland ML, Wechsler J, Bensussan A, Boumsell L: Functional role of CD101 on skin dendritic cells. Adv Exp Med Biol. 1997;417:227-32.
PubMed
Grassi F, Dezutter-Dambuyant C, McIlroy D, Jacquet C, Yoneda K, Imamura S, Boumsell L, Schmitt D, Autran B, Debré P, Hosmalin A: Monocyte-derived dendritic cells have a phenotype comparable to that of dermal dendritic cells and display ultrastructural granules distinct from Birbeck granules. J Leukoc Biol. 1998 Oct;64(4):484-93.
PubMed
Variant
0.1 mg
11-778-C100
In stock
143.00 USD

0.025 mg
11-778-C025
Delivery 1 week
71.50 USD
Variant
0.1 mg
11-778-C100
In stock
143.00 USD

0.025 mg
11-778-C025
Delivery 1 week
71.50 USD

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