Anti-Blood Group ABH Culture supernatant

Anti-Blood Group ABH Culture supernatant
Regulatory status
RUO
Antigen
Blood Group ABH
Clone
HE-10
Format
Culture supernatant
Reactivity
Human
Application
IHC(P)
Variant
1.0 ml
99-812-L001
In stock
Variant
0.1 mg
11-261-C100
In stock
Product details
References
Isotype
Mouse IgM
Specificity
The antibody HE-10 agglutinates erythrocytes of group A, and is excellent as a tumour marker in patients of blood group B and 0. It does not agglutinate erythrocytes of group B and 0. Study with specific oligosaccharides showed that the antibody HE-10 reacts with A and H antigens with chain types 3 and 4 and it does not react with A disaccharide, A trisaccharide, A type 1, A type 2, ALeb. The antibody HE-10 does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues.
Application
IHC(P)
Reactivity
Human
Immunogen
Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.
Preparation
The hybridoma culture supernatant is 4 x concentrated by ultrafiltration using 100 kDa-cut off membrane.
Formulation
Culture supernatant
Storage and handling
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Exbio licence note
Unless indicated otherwise, all products are For Research Use Only and not for diagnostic use. In vivo diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s. © 2019 EXBIO Praha, a.s. All rights reserved.

Product specific references:

Nemec M, Drimalova D, Horejsi V, Vanak J, Bartek J, Viklicky V: Murine monoclonal antibodies to human A erythrocytes: differential reactivity with N-acetyl-D-galactosamine. Vox Sang. 1987;52(1-2):125-8.
PubMed
Vanak J, Drimalova D, Smyslova O, Nemec M, Viklicky V, Wisniewski K: Detection of blood group A antigen expression in human colon cancer using monoclonal antibodies with different specificities. Neoplasma. 1989;36(4):479-88.
PubMed
Variant
1.0 ml
99-812-L001
In stock
Variant
0.1 mg
11-261-C100
In stock