CD4 FITC

CD4 FITC
Regulatory status
CE IVD
Format
FITC
Reactivity
Human
Application
FC (QC tested)
Excitation laser
blue (488 nm)
Variant
100 tests
ED7013
In stock
180.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD
Product details
References
Application
FC (QC tested)
Reactivity
Human
Description
The reagent CD4 FITC permits identification and enumeration of cell populations expressing human CD4 antigen in whole blood using flow cytometry.
Contents
The reagent contains mouse monoclonal antibody against human CD4 antigen (clone MEM-241) which was purified by affinity chromatography and labeled with Fluorescein isothiocyanate (FITC). The labeled antibody is diluted in an optimal concentration in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide. The content of a vial (2 ml) is sufficient for 100 tests.
Preparation
The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended for In Vitro Diagnostic Use. In vivo diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Product specific references:

Yi H et al. (2006) The phenotypic characterization of naturally occurring regulatory CD4+CD25+ T cells. Cell Mol Immunol. 3: 189-195
Zola H et al. (2006) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 319: 1-5
Huang Y and Wange RL (2004) T cell receptor signaling: beyond complex complexes. J Biol Chem. 279: 28827-28830 Nakamura Y et al. (2004) Intrathyroidal CD4+ T lymphocytes express high levels of Fas and CD4+CD8+macrophages/dendritic cells express Fas ligand in autoimmune thyroid disease. Thyroid 14: 819-824
Brdickova N. et al. (2003) LIME: a new membrane Raftassociated adaptor protein involved in CD4 and CD8 coreceptor signaling. J Exp Med. 198:1453-62
Clapham PR and McKnight A (2002) Cell surface receptors, virus entry and tropism of primate lentiviruses. J Gen Virol. 83: 1809-29
Foti M et al. (2002) p56Lck anchors CD4 to distinct microdomains on microvilli. Proc Natl Acad Sci U S A. 99: 2008-13
Nam K-H et al. (2000) Peripheral blood extrathymic CD4+CD8+ T cells with high cytotoxic activity are from the same lineage as CD4+CD8- T cells in cynomolgus monkeys. Int Immunol. 12: 1095-1103
Millan J et al. (1999) CD4 segregates into specific detergentresistant T-cell membrane microdomains. Tissue Antigens. 53: 33-40
Variant
100 tests
ED7013
In stock
180.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD