CD8 FITC

CD8 FITC
Regulatory status
CE IVD
Antigen
CD8
Format
FITC
Reactivity
Human
Application
FC (QC tested)
Excitation laser
blue (488 nm)
Variant
100 tests
ED7004
In stock
180.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD
Product details
References
Application
FC (QC tested)
Reactivity
Human
Description
The reagent CD8 FITC permits identification and enumeration of cell populations expressing human CD8 antigen in whole blood using flow cytometry.
Contents
The reagent contains mouse monoclonal antibody against human CD8 antigen (clone MEM-31) which was purified by affinity chromatography and labeled with Fluorescein isothiocyanate (FITC). The labeled antibody is diluted in an optimal concentration in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide. The content of a vial (2 ml) is sufficient for 100 tests.
Preparation
The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended for In Vitro Diagnostic Use. In vivo diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.

Product specific references:

van den Berg HA et al. (2007) Coreceptor CD8-driven modulation of T cell antigen receptor specificity. J Theor Biol. 249: 395-408
Pang DJ et al. (2007) CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, not CD8alpha alpha homodimers. J Biol Chem. 282: 13884-94
Devine L et al. (2006) Mapping the binding site on CD8 beta for MHC class I reveals mutants with enhanced binding. J Immunol. 177: 3930-8
Horejsi V et al. (1988): Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74). Folia Biol (Praha). 34: 23-34
Horejsi V. et al. (1986) Monoclonal antibodies against human leucocyte antigens. I. Antibodies against beta-2-microglobulin, immunoglobulin kappa light chains, HLA-DR-like antigens, T8 antigen, T1 antigen, a monocyte antigen, and a pan-leucocyte antigen. Folia Biol. (Praha) 32, 12
Leukocyte Typing III., McMichael A. J. et al (Eds.), Oxford University Press (1987).
Variant
100 tests
ED7004
In stock
180.00 USD
Variant
0.1 mg
11-261-C100
In stock
180.00 USD