Blog

New challengies in the diagnostics of allergies

Intended use: Development of qualitative and quantitative allergy tests and assays for assesment of patients reactivity profiles or follow up of allergic patients during immunotherapy.

In addition to ACE2 and TMPRSS2, also other host cell surface proteins may be involved in the interactions with the SARS-CoV-2 virus. It has been known since 2005 that broadly expressed transmembrane glycoprotein of the immunoglobulin superfamily CD147 (also known as basigin or EMMPRIN) facilitates SARS-CoV invasion for host cells.
 
Here we present a short communication of Prof. Vaclav Horejsi, PhD (IMG AS CR) on this Hot Topic.

EXBIO has recently developed two new products for multicolor flow-cytometric immunophenotyping of cells of the human immune system from peripheral blood to follow up kinetics of immune responses in relation to clinical and virological features of a COVID-19 patients.
Now, we bring you a presentation of patient’s data – comparision with percentage range acquired from normal healthy donors and time-course changes in subpopulations of B and T cells of hospitalized patients diagnosed with COVID-19.

While the COVID-19 pandemic rises exponentially influencing daily life of all of us, EXBIO decided to face the situation and focus all our effort on development of two Dry Reagent kits for cytometric analysis of T and B cell populations. Our goal was to provide all laboratories  with an efficient, reliable and fast tool for analyzing carefully selected cellular subpopulations important for characterizing the patient's samples. 

EXBIO is proud to inform you, that recently a paper with title: "High-sensitivity 5-, 6-, and 7-color PNH WBC assays for both Canto II and Navios platforms." was published in Cytometry B.

One of authors of this paper is EXBIO Flow Cytometry Expert Miro Benko.

Antibody to CD138 conjugated with Pacific Orange™ is being used in standardized flow cytometry panels (clone B-A38).

Here we show that the clone MI15 in Pacific Orange™ provides fully comparable results to those obtained using B-A38.