Today we introduce one rat and two mouse monoclonal antibody clones, that have been added to our portfolio: Anti-human CD172g (clone OX-119), anti-alpha tubulin (YOL1/34), and anti-BCL6 (clone IG191E/A8).
When performing immunostaining procedures, it is important to know also the backround signal of the immunoglobulin itself, especially when higher antibody concentrations are being used. Hence negative controls represented by conjugates of corresponding antibody isotypes are available.
Easy way how to identify regulatory T cells (Tregs) in human peripheral blood or umbilical cord blood.
Determination of cytokeratine content has become an important tool in classification of tumor cells. The patterns of cytokeratins of a given type of carcinoma appear to be identical in primary tumors and metastases, independent from the specific location and size.
Recombinant allergens are produced both in prokaryotic (mainly E. coli) and in eukaryotic (yeast and insect cells) expression systems and in addition to their use in diagnostics find their way also into immunotherapy of various allergies.
The mouse monoclonal antibody JOVI.1, recognizing an extracellular epitope on TCR Cbeta1 (TRBC1), is suitable for flow cytometry, immunoprecipitation, and immunohistochemistry (frozen sections). It is popular as a tool for analysis of T cell-mediated diseases.
We are proud to inform you that in March 2020 in Cytometry B (Clinical cytometry) a paper was released having one of our colleagues from EXBIO Praha team Miro Benko (Director, Product Development Department) as a co-author.
Recently developed strategy for prevention of cancer relapse due to acquired radioresistance may be based on immunotherapies. One promising approach is based on genetically modified T cells expressing chimeric antigen receptors (CAR).