Recombinant allergens

New challengies in the diagnostics of allergies


IMG_4374.JPGAllergen sequence selection: AA sequence of all EXBIO allergens were selected accordingly to data presented on the official site for systematic allergen nomenclature (www.allergen.org, approved by WHO/IUIS*).

High purity: Advantage of recombinant allergens, compared to allergen extracts, is that they do not contain non-allergenic impurities or contamination by other allergens, which could possibly lead to false-positive results. Recombinant allergens are produced in appropriate expression systems, accordingly to the nature of each particular allergen, followed by at least 2 sequential chromatography purification steps, to ensure high product purity.

Lot-to-lot consistency: Reagent packagings of recombinant allergens contain precisely defined amount of specific protein, compared to allergen extracts, which suffer from high variability between lots (this applies particularly for allergens concentration in the mix and their ratio). Lot-to-lot consistency is ensured by outstanding level of product development, manufacture and QC control (ISO 9001:2015 certified Quality Management System).

Intended use: Development of qualitative and quantitative allergy tests and assays for assesment of patients reactivity profiles or follow up of allergic patients during immunotherapy. Application: Recombinant allergens are intended for ELISA application. Other applications than ELISA must be verified by the user. BULK amounts available for the development of allergen specific diagnostic tests.

LIST OF AVAILABLE RECOMBINANT ALLERGENS here

Are you looking for any recombinat allergen, currently not available from EXBIO? Please contact our sales team at info@exbio.cz

Manufactured by Apronex Ltd., an EXBIO company.

* WHO/IUIS ... World Health Organisation, International Union of Immunological Societes.