CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.
Anti-Hu CD52 Purified
Anti-hu CD52 FITC (Cat. No.: 1F-878-C100)
Anti-hu CD52 PE (Cat. No.: 1P-878-C100)
Anti-hu CD52 APC (Cat. No.: 1A-878-C100)
Fig. 1: Separation of lymphocytes stained with anti-human CD52 (4C8) purified antibody (concentration in the sample 0.6 μg/ml, GAM APC, red-filled) from lymphocytes unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).
CLEC2 (C-type lectin-like receptor 2) functions as a platelet receptor for the lymphatic endothelial marker, PDPN, and mediates platelet activation. Besides platelets, it can be found on myeloid cells and NK cells. CLEC2 functions also as an attachment factor for HIV-1 and facilitates its capture by platelets.
Anti-Hu CLEC2 Purified
Anti-Hu CLEC2 Purified PE (Cat. No.: 1P-892-T100)
Fig. 2: Separation of human CLEC2 positive thrombocytes (red-filled) from human lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human CLEC2 (AYP1) purified antibody (concentration in the sample 1.7 μg/ml, GAM APC).
Approaching closer to the May 2022 deadline where all IVD products marketed in the EU must meet the new IVDR regulations, we are pleased to confirm to you our active steps to receive “EU Quality Management System Certificate (IVDR)” from the Notified body under the new IVDR on timely fashion.
TdT (terminal deoxynucleotidyl transferase) is a widely used marker in the diagnosis of leukemias.
We are introducing a set of antibodies for identification of p63 and p73 isoforms, which have relevance for tumor analysis.