System Certification ISO 9001:2000
Exbio Antibodies CZ / SK eShop
a-z list

Native human Prostate-specific antigen / PSA

Technical Information Request    Inquiry for Bulk Prices

Product No. Form Quantity Stock Price Datasheet Shop
  EXB0011 Lyophilized 0.1 mg yes choose region PDF datasheetHTML datasheet buy
- In stock! Ready for immediate despatch - Manufacture on order

Source

Prostate-specific antigen (PSA) was purified from human seminal plasma by ion-exchange chromatography and gel filtration. The purified antigen was dialyzed against d.H2O and lyophilized.

Description

Prostate-specific antigen (PSA) is a glycoprotein of approx. 30 kDa found mainly in prostatic tissue and seminal fluid; it is produced by normal prostate cells. The molecule consists of approximately 92% protein and 8% carbohydrate. This enzyme participates in the dissolution of the seminal fluid coagulum and plays an important role in fertility. The highest amounts of PSA are found in the seminal fluid; some PSA escapes the prostate and can be found in the serum. This serum component has been used to track the response to therapy in men with prostate cancer.

Regulatory Status

Database Links


Applications:

  • Positive control
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

General references

  • *Zhang WM, Leinonen J, Kalkkinen N, Dowell B, Stenman UH: Purification and characterization of different molecular forms of prostate-specific antigen in human seminal fluid. Clin Chem. 1995 Nov;41(11):1567-73. [Abstract]
  • For research use only. Not for drug, diagnostic or other use.

    Related Products

  • Mouse Monoclonal to Prostate-specific antigen (PSA) A67-B/E3 (IgG1)
  • Mouse Monoclonal to Prostate-specific antigen (PSA) A67-B/E3 (IgG1)
  • Example Data


    PSA antigen
    Fig. 1. Western Blotting


    Fig.1. Western Blotting analysis of native human Prostate-specific antigen (cat. no. EXB0011; previously NL-008-C100). Reducing conditions.
    Lane 1-3: immunostaining of PSA antigen (1 mg/ml) with anti-human Prostate-specific antigen antibody (A67-B/E3; EXBIO cat. no. 11-289-C100; dilution 1 μg/ml (1), 0.5 μg/ml (2), 0.2 μg/ml (3)). Detection by Goat anti-mouse / HRP secondary antibody.

    Unless indicated otherwise, all products are For Research Use Only and not for diagnostic or therapeutic use. Not for resale or transfer either as a stand-alone product or as a component of another product without written consent of EXBIO. EXBIO will not be held responsible for patent infringement or other violations that may occur with the use of our products. All orders are accepted subject to EXBIO´s term and conditions which are available at www.exbio.cz.
    © 2003 EXBIO. All rights reserved.
    terms and conditions | privacy policy