System Certification ISO 9001:2000
Exbio Antibodies CZ / SK eShop
by categories | a-z list | Application type: Flow Cytometry | Immunohistochemistry | Functional Studies
Antigen Clone Application
CD102 / ICAM-2 CBR-IC2/2 blocking
CD11a MEM-83 The antibody MEM-83 directly induces the binding of T cells to purified ICAM-1. Using an in vitro-translated CDlla cDNA deletion series, the MEM-83 activation epitope was mapped to the "I" domain of the LFA-1 alpha subunit. The studies have therefore identified a novel LFA-1 activation epitope mapping to the I domain of LFA-1, which could play a role in the regulation of LFA-1 binding to ICAM-1.
CD11a MEM-25 The antibody MEM-25 partially blocks binding of LFA-1 complex to ICAM-1.
CD11a (mouse) M17/4 Blocking
CD11b ICRF44 blocking of granulocyte activation
CD11b MEM-170 The antibody MEM-170 blocks (not completely) Mac-1-mediated neutrophil binding to fibrinogen.
CD11b activation epitope CBRM1/5 blocking
CD11b (mouse) M1/70 In vitro blocking of CD11b
CD120a H398 blocking
CD122 TU27 blocking
CD129 / IL-9R alpha AH9R7 blocking
CD13 WM15 The antibody WM15 inhibits infection of cells by human coronavirus and inhibits aminopeptidase N activity of the CD13 molecule immunoprecipitates.
CD137 / 4-1BB 4B4-1 inhibition of cytokine production
CD14 MEM-18 The antibody MEM-18 completely blocks binding of fluorescein (FITC) – labeled bacterial LPS to the monocyte surface and it also blocks the binding of CD14 to the extracellular TLR2 domain.
CD142 HTF-1 blocking
CD147 MEM-M6/6 The antibody MEM-M6/6 (high-affinity mAb of unique epitope specificity) inhibits anti-CD3-induced T cell activation.
CD151 50-6 blocking
CD154 / CD40L 24-31 blocking
CD154 / CD40L (mouse) MR-1 Blocking T cell costimulation in vivo.
CD158d / KIR2DL4 mAb#33 Cytokine secretion studies
CD16 MEM-154 The antibody MEM-154 blocks binding of human IgG to FcgammaRIII.
CD16 3G8 In vitro Stimulation of NK cell proliferation, blocking of IgG binding and phagocytosis, inhibition of cytotoxic activity, in vivo NK cell depletion
CD169 / Siglec-1 7-239 inhibition of erythrocyte rosetting with cells expressing cd169
CD178 / Fas-L NOK-1 blocking
CD18 MEM-148 The antibody MEM-148 induces homotypic cell aggregation and high-affinity LFA-1 conformation in resting leukocytes.
CD18 MEM-48 The antibody MEM-48 induces high-affinity conformation of LFA-1 complex.
CD18 (mouse) M18/2 Blocking or stimulation
CD180 G28-8 induction of B cell proliferation
CD184 / CXCR4 12G5 blocking
CD19 (mouse) 1D3 This antibody can induce down-regulation of CD19, affecting the proportions of B cell subpopulations.
CD2 TS1/8 blocking
CD200 OX-104 blocking
CD206 15-2 blocking
CD229 HLy9.25 Regulation of activation
CD243 UIC2 inhibition
CD25 (mouse) PC61.5 In vitro blocking of IL-2 binding to its receptor (CD25) and inhibition of IL-2 stimulated cell growth. In vivo depletion of CD25 positive cells.
CD253 / TRAIL 2E5 The antibody 2E5 has high neutralizing activity for human TRAIL in biological assays.
CD255 / TWEAK CARL-1 neutralization
CD261 / TRAIL-R1 DR-4-02 Soluble antibody DR-4-02 blocks apoptosis triggered by a ligand (TRAIL).
Plastic-immobilized (cross-linked) DR-4-02 antibody induces apoptosis in sensitive cells.
Recommended dilution of antibody: 2-3 μg/ml in cultivation medium
Final concentration of TRAIL: 20-200 ng/ml
Application note: It is recommended to add the antibody 15 min before addition of TRAIL.
CD266 / TWEAK R ITEM-4 blocking
CD273 / PD-L2 24F.10C12 blocking
CD274 / PD-L1 29E.2A3 blocking
CD279 / PD-1 EH12.2H7 blocking
CD28 CD28.2 T cell costimulation
CD28 (mouse) 37.51 In vitro and in vivo T cell costimulation
CD28 (rat) JJ319 in vitro costimulation
CD3 UCHT1 The immobilized UCHT1 antibody initiates a signaling pathway resulting in T cell activation and proliferation.
CD3 OKT3 counteracting both generation and function of effector T cells
CD3 MEM-57 The antibody MEM-57 has strong mitogenic effect on peripheral T lymphocytes; it reacts strongly with gamma/delta T lymphocytes.
CD3 MEM-92 The antibody MEM-92 in solution induces early responses of T cell activation (tyrosine phosphorylation, calcium elevation, Erk activation and expression of activation antigens), but it is unable to induce T cell proliferation.
CD3 (mouse) 145-2C11 Induction of T cell activation, proliferation or apoptosis (depending on conditions); in vivo T cell depletion
CD300e UP-H2 stimulation
CD314 1D11 blocking of ligand binding
CD33 WM53 Induction of cytokine production
CD34 QBEnd-10 The antibody QBEnd-10 induces homotypic adhesion of leukemic cell line.
CD4 EM4 blocking
CD4 MEM-115 The antibody MEM-115 blocks binding of HIV gp120 to CD4 molecule and it also strongly inhibits CD4-MHC Class II interactions.
CD4 (mouse) GK1.5 Isolation and depletion of CD4+ T cells, blocking of ligand binding to CD4.
CD41 (mouse) MWReg30 platelet depletion
CD42b HIP1 The antibody HIP1 inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets and ristocetin-induced platelet agglutination.
CD43 MEM-59 The antibody MEM-59 activates T lymphocytes and also induces apoptosis in hemopoietic progenitor cells.
CD45 HI30 blocking CD45 functions
CD45R (human, mouse) RA3-6B2 modulation of B cell responses
CD49d / Integrin alpha 4 9F10 in vitro T cell costimulation
CD50 MEM-04 The antibody MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1).
CD53 MEM-53 The antibody MEM-53 induces activation of monocytes and B lymphocytes.
CD54 (mouse) YN1/1.7.4 Blocking
CD59 MEM-43 blocking
CD59 MEM-129 The antibody MEM-129 activates T cells.
CD62L DREG56 Particularly effective in blocking of lymphocyte CD62L-mediated binding to peripheral lymph node HEV
CD62L / L-Selectin (mouse) MEL-14 Blocking of cell adhesion
CD62P AK4 Blocking
CD64 10.1 blocking of IgG binding to the FcgammaR1
CD69 FN50 When stimulating peripheral blood T cells, FN50 antibody together with TPA synergistically increases cell volume and RNA/DNA synthesis. Addition of FN50 to stimulated peripheral blood B cells has similar, but weaker effect.
CD8a (mouse) 53-6.7 Isolation and depletion of CD8+ cells, blocking of cytotoxicity, inhibition of CD8+ T cell proliferation.
CD8a (rat) OX-8 blocking
CD8b (rat) 341 Macrophage stimulation, in vitro blocking of allogenic responses
CD80 16-10A1 Blocking
CD81 M38 In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
CD82 C33 In human MOLT-4 T-cell line the antibody C33 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
CD84 CD84.1.21 Enhancement of CD3-induced IFN-gamma production
CD85g / ILT7 17G10.2 activation
CD85j / ILT2 GHI/75 blocking HLA-G induced TGF-beta1 production
CD86 BU63 The antibody BU63 blocks mixed lymphocyte reaction (MLR) and binding of soluble CTLA-4 (CD152)-mulg fusion protein to CD86 (B7-2).
CD86 (mouse) GL-1 Blocking
CD9 MEM-61 The antibody MEM-61 induces FcγR-dependent platelet aggregation.
CD9 (bovine) IVA50 The antibody IVA50 activates bovine thrombocytes.
CD90.2 / Thy-1.2 (mouse) 1aG4/C5 The bound of antibody 1aG4/C5 to the transfected mast cells induces the activation processes which are similar, but not identical, to the antigen activation of IgE stimulated cells.
Other studies approve that the antibody 1aG4/C5 precipitates complexes with Lyn protein tyrosine kinase.
CD95 / Fas UT-1 The antibody UT-1 induces Fas-mediated apoptosis.
CD95 / Fas EOS9.1 in vitro induction of apoptosis
Cyclin D1 DCS-6 blocking
DLL4 MHD4-46 blocking
HIV protease 1696 The antibody 1696 strongly inhibits the enzyme activity of HIV-1 and HIV-2 proteases.
HLA-Class I W6/32 The antibody W6/32 is suitable as a positive control for HLA tissue typing.
HLA-DR L243 blocking
HLA-G 87G Application note: The antibody 87G blocks interaction of HLA-G with inhibitory receptors.
IFN-gamma 4S.B3 Neutralization (weak)
IFN-gamma NIB42 neutralization
Insulin IN-05 The antibody IN-05 blocks binding of insulin to the receptor.
Ly6G (mouse) RB6-8C5 Neutrophil depletion
MHC Class II (mouse) M5/114 Blocking of T cell proliferative responses
NK1.1 / CD161bc (mouse) PK136 in vivo depletion of NK cells and NK-T cells
TCR alpha/beta (rat) R73 in vitro activation and in vivo depletion of TCR alpha/beta T cells
TCR beta (mouse) H57-597 In vitro T cell stimulation; In vivo T cell depletion
TCR beta (Vbeta5.3-related) MEM-262 Activates T cells (V beta 5-related subset)
TCR gamma/delta B1 blocking
TCR gamma/delta (rat) V65 in vitro activation, in vivo depletion of gamma/delta T cells
TNF-alpha MAb1 neutralization
TNF-alpha MAb11 neutralization
Transferrin HTF-14 The antibody HTF-14 blocks binding of transferrin to the receptor.

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