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Rabbit Polyclonal to Mycobacterium tuberculosis antigen Tb10.3

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Background

The Mycobacterium tuberculosis antigen Tb10.3, also known as EsxR, ESAT-6 like protein 9 (ES6_9), or Rv3019c, is an almost uncharacterized conserved bacterial protein.

Specificity

The rabbit polyclonal antibody to Tb10.3 reacts with Mycobacterium tuberculosis protein Tb10.3 (EsxR).

Regulatory Status

Immunogen

Recombinant Mycobacterium tuberculosis Tb10.3 produced in E. coli

Species Reactivity:

  • Mycobacterium tuberculosis

Negative Species:

Applications:

  • Western Blotting
  • ELISA
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

General references

  • *Billeskov R, Vingsbo-Lundberg C, Andersen P, Dietrich J: Induction of CD8 T cells against a novel epitope in TB10.4: correlation with mycobacterial virulence and the presence of a functional region of difference-1. J Immunol. 2007 Sep 15;179(6):3973-81. [Abstract] [Full Text]
  • *Skjøt RL, Brock I, Arend SM, Munk ME, Theisen M, Ottenhoff TH, Andersen P: Epitope mapping of the immunodominant antigen TB10.4 and the two homologous proteins TB10.3 and TB12.9, which constitute a subfamily of the esat-6 gene family. Infect Immun. 2002 Oct;70(10):5446-53. [Abstract] [Full Text]
  • For research use only. Not for drug, diagnostic or other use.

    Example Data

    anti-Tb10.3
    Fig. 1


    Fig. 1. Western blotting analysis of polyclonal anti-Mycobacterium tuberculosis antigen Tb10.3.
    A) cell lysate of non-transfected E. coli
    B) cell lysate of Tb10.3-transfected E. coli

    Unless indicated otherwise, all products are For Research Use Only and not for diagnostic or therapeutic use. Not for resale or transfer either as a stand-alone product or as a component of another product without written consent of EXBIO. EXBIO will not be held responsible for patent infringement or other violations that may occur with the use of our products. All orders are accepted subject to EXBIO´s term and conditions which are available at www.exbio.cz.
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