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Mouse Monoclonal to CD165

SN2 (IgG1)

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  11-165-C100 purified 0.1 mg yes choose region PDF datasheetHTML datasheet buy
  1P-165-T025 PE 25 tests yes choose region PDF datasheetHTML datasheet buy
  1P-165-T100 PE 100 tests yes choose region PDF datasheetHTML datasheet buy
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CD165 is a poorly characterized transmembrane protein highly expressed on platelets and many leukemic T cell lines. At lower level it is expressed on a proportion of circulating T cells and monocytes, on thymic epithelium, fibroblasts, epidermal keratinocytes, pancreatic islet cells, and some neurons. It might have a role in adhesion between thymocytes and thymic epithelial cells and it can be used as a marker for tumor progression.


The mouse monoclonal antibody SN2, also known as SN2 N6-D11, recognizes CD165, an approximately 37-42 kDa transmembrane glycoprotein expressed mainly on leukemic T cells, double positive and double negative thymocytes (CD4-CD8-, CD4+CD8+), and platelets.
HLDA VI: WS Code N-L099

Regulatory Status


CD165 purified from human Molt-4 cell line

Species Reactivity:

  • Human

Negative Species:


  • Flow Cytometry
  • Immunoprecipitation
  • Western Blotting
  • Immunohistochemistry (frozen sections)
    Application note: acetone fixation
  • Immunocytochemistry
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *Seon BK, Negoro S, Barcos MP, Tebbi CK, Chervinsky D, Fukukawa T: Monoclonal antibody SN2 defining a human T cell leukemia-associated cell surface glycoprotein. J Immunol. 1984 Apr;132(4):2089-95. [Abstract]
  • *Seon BK: Specific killing of human T-leukemia cells by immunotoxins prepared with ricin A chain and monoclonal anti-human T-cell leukemia antibodies. Cancer Res. 1984 Jan;44(1):259-64. [Abstract]
  • For research use only. Not for drug, diagnostic or other use.

    Example Data

    SN2 purified

    Fig. 1. Surface staining of CD165 on JURKAT cells with anti-CD165 (SN2) purified, GAM-APC.

    SN2 PE

    Fig. 2. Surface staining of CD165 on JURKAT cells with anti-CD165 (SN2) PE.

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