System Certification ISO 9001:2000
Exbio Antibodies CZ / SK eShop
by categories | a-z list | Application type: Flow Cytometry | Immunohistochemistry | Functional Studies

Mouse Monoclonal to CD102 / ICAM-2

CBR-IC2/2 (IgG2a)

Technical Information Request    Inquiry for Bulk Prices

Product No. Form Quantity Stock Price Datasheet Shop
  11-148-C025 purified 0.025 mg yes choose region PDF datasheetHTML datasheet buy
  11-148-C100 purified 0.1 mg yes choose region PDF datasheetHTML datasheet buy
  1P-148-T025 PE 25 tests yes choose region PDF datasheetHTML datasheet buy
  1P-148-T100 PE 100 tests yes choose region PDF datasheetHTML datasheet buy
- In stock! Ready for immediate despatch - Manufacture on order


CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.


The mouse monoclonal antibody CBR-IC2/2 recognizes CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.
HLDA V; WS Code BP363

Regulatory Status


Human CD102 cDNA transfected COS cells

Species Reactivity:

  • Human

Negative Species:


  • Flow Cytometry
  • Immunoprecipitation
  • Immunohistochemistry (frozen sections)
  • Functional Application
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *de Fougerolles AR, Stacker SA, Schwarting R, Springer TA: Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1. J Exp Med. 1991 Jul 1;174(1):253-67. [Abstract] [Full Text]
  • *Kawamata N, Xu B, Nishijima H, Aoyama K, Kusumoto M, Takeuchi T, Tei C, Michie SA, Matsuyama T: Expression of endothelia and lymphocyte adhesion molecules in bronchus-associated lymphoid tissue (BALT) in adult human lung. Respir Res. 2009 Oct 22;10:97. doi: 10.1186/1465-9921-10-97. [Abstract] [Full Text]
  • *Maki G, Krystal G, Dougherty G, Takei F, Klingemann HG: Induction of sensitivity to NK-mediated cytotoxicity by TNF-alpha treatment: possible role of ICAM-3 and CD44. Leukemia. 1998 Oct;12(10):1565-72. [Abstract]
  • *Diacovo TG, deFougerolles AR, Bainton DF, Springer TA: A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2. J Clin Invest. 1994 Sep;94(3):1243-51. [Abstract] [Full Text]
  • *Juan M, Mullol J, Roca-Ferrer J, Fuentes M, Pérez M, Vilardell C, Yagüe J, Picado C: Regulation of ICAM-3 and other adhesion molecule expressions on eosinophils in vitro. Effects of dexamethasone. Allergy. 1999 Dec;54(12):1293-8. [Abstract]
  • *de Fougerolles AR, Springer TA: Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. J Exp Med. 1992 Jan 1;175(1):185-90. [Abstract] [Full Text]
  • For research use only. Not for drug, diagnostic or other use.

    Example Data


    Fig. 1. Surface staining of human peripheral blood with anti-human CD102 (CBR-IC2/2) purified, GAM-APC.

    Unless indicated otherwise, all products are For Research Use Only and not for diagnostic or therapeutic use. Not for resale or transfer either as a stand-alone product or as a component of another product without written consent of EXBIO. EXBIO will not be held responsible for patent infringement or other violations that may occur with the use of our products. All orders are accepted subject to EXBIO´s term and conditions which are available at
    © 2003 EXBIO. All rights reserved.
    terms and conditions | privacy policy