System Certification ISO 9001:2000
Exbio Antibodies CZ / SK eShop
by categories | a-z list | Application type: Flow Cytometry | Immunohistochemistry | Functional Studies

Mouse Monoclonal to CD61

VIPL2 (IgG1)

Technical Information Request    Inquiry for Bulk Prices

Product No. Form Quantity Stock Price Datasheet Shop
  11-647-C025 purified 0.025 mg yes choose region PDF datasheetHTML datasheet buy
  11-647-C100 purified 0.1 mg yes choose region PDF datasheetHTML datasheet buy
  1F-647-T025 FITC 25 tests yes choose region PDF datasheetHTML datasheet buy
  1F-647-T100 FITC 100 tests yes choose region PDF datasheetHTML datasheet buy
  1P-647-T025 PE 25 tests yes choose region PDF datasheetHTML datasheet buy
  1P-647-T100 PE 100 tests yes choose region PDF datasheetHTML datasheet buy
  1A-647-T025 APC 25 tests yes choose region PDF datasheetHTML datasheet buy
  1A-647-T100 APC 100 tests yes choose region PDF datasheetHTML datasheet buy
  PC-647-T025 PerCP 25 tests yes choose region PDF datasheetHTML datasheet buy
  PC-647-T100 PerCP 100 tests yes choose region PDF datasheetHTML datasheet buy
  T7-647-T025 PE-Cy™7 25 tests yes choose region PDF datasheetHTML datasheet buy
  T7-647-T100 PE-Cy™7 100 tests yes choose region PDF datasheetHTML datasheet buy
  T4-647-T025 APC-Cy™7 25 tests yes choose region PDF datasheetHTML datasheet buy
  T4-647-T100 APC-Cy™7 100 tests yes choose region PDF datasheetHTML datasheet buy
- In stock! Ready for immediate despatch - Manufacture on order

Background

CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.

Specificity

The mouse monoclonal antibody VIPL2 recognizes CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.
HLDA V.; WS Code 5T-124

Regulatory Status

Species Reactivity:

  • Human
  • Non-Human Primates

Negative Species:

Applications:

  • Flow Cytometry
  • Western Blotting
  • Immunohistochemistry (frozen sections)
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *Dzionek A, Fuchs A, Schmidt P, Cremer S, Zysk M, Miltenyi S, Buck DW, Schmitz J: BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol. 2000 Dec 1;165(11):6037-46. [Abstract] [Full Text]
  • *Mondal D, Williams CA, Ali M, Eilers M, Agrawal KC: The HIV-1 Tat protein selectively enhances CXCR4 and inhibits CCR5 expression in megakaryocytic K562 cells. Exp Biol Med (Maywood). 2005 Oct;230(9):631-44. [Abstract] [Full Text]
  • *Williams CA, Mondal D, Agrawal KC: The HIV-1 Tat protein enhances megakaryocytic commitment of K562 cells by facilitating CREB transcription factor coactivation by CBP. Exp Biol Med (Maywood). 2005 Dec;230(11):872-84. [Abstract] [Full Text]
  • *Ciarlet M, Crawford SE, Cheng E, Blutt SE, Rice DA, Bergelson JM, Estes MK: VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment. J Virol. 2002 Feb;76(3):1109-23. [Abstract] [Full Text]
  • *Barrett L, Dai C, Gamberg J, Gallant M, Grant M: Circulating CD14-CD36+ peripheral blood mononuclear cells constitutively produce interleukin-10. J Leukoc Biol. 2007 Jul;82(1):152-60. [Abstract] [Full Text]
  • *Roberts MS, Woods AJ, Dale TC, Van Der Sluijs P, Norman JC: Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins. Mol Cell Biol. 2004 Feb;24(4):1505-15. [Abstract] [Full Text]
  • For research use only. Not for drug, diagnostic or other use.

    Example Data

    VIPL2 PE-Cy7


    Fig. 1. Surface staining of human peripheral blood with anti-human CD61 (VIPL2) PE-CyTM7.


    VIPL2 APC


    Fig. 2. Surface staining of human peripheral blood with anti-human CD61 (VIPL2) APC.


    VIPL2 APC-Cy7


    Fig. 3. Surface staining of human peripheral blood with anti-human CD61 (VIPL2) APC-CyTM7.


    VIPL2 PE FC


    Fig. 4. Surface staining of human peripheral blood with anti-human CD61 (VIPL2) PE.


    VIPL2 PerCP


    Fig. 5. Surface staining of human peripheral blood with anti-human CD61 (VIPL2) PerCP.



    VIPL2 FITC


    Fig. 6. Surface staining of human peripheral blood with anti-human CD61 (VIPL2) FITC.

    Unless indicated otherwise, all products are For Research Use Only and not for diagnostic or therapeutic use. Not for resale or transfer either as a stand-alone product or as a component of another product without written consent of EXBIO. EXBIO will not be held responsible for patent infringement or other violations that may occur with the use of our products. All orders are accepted subject to EXBIO´s term and conditions which are available at www.exbio.cz.
    Alexa Fluor®, Pacific Blue™ and Pacific Orange™ are registred trademarks of Molecular Probes Inc., Eugene, OR, USA. (licence label)
    DyLight® is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
    Cy™ and CyDye™ are registered trademarks of GE Healthcare.
    © 2003 EXBIO. All rights reserved.
    terms and conditions | privacy policy