Species Reactivity:
- Mouse
- Rat
- Other species Not tested
Negative Species:
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Applications:
- Western Blotting
- Immunocytochemistry
Usage note: Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.
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General references
*Fritschy JM, Meskenaite V, Weinmann O, Honer M, Benke D, Mohler H: GABAB-receptor splice variants GB1a and GB1b in rat brain: developmental regulation, cellular distribution and extrasynaptic localization. Eur J Neurosci. 1999 Mar;11(3):761-8. [Abstract]
*Galvez T, Duthey B, Kniazeff J, Blahos J, Rovelli G, Bettler B, Prézeau L, Pin JP: Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function. EMBO J. 2001 May 1;20(9):2152-9. [Abstract] [Full Text]
*Ng GY, Bertrand S, Sullivan R, Ethier N, Wang J, Yergey J, Belley M, Trimble L, Bateman K, Alder L, Smith A, McKernan R, Metters K, O'Neill GP, Lacaille JC, Hébert TE: Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant
gabapentin action. Mol Pharmacol. 2001 Jan;59(1):144-52. [Abstract] [Full Text]
*Margeta-Mitrovic M, Jan YN, Jan LY: Ligand-induced signal transduction within heterodimeric GABA(B) receptor. Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14643-8. [Abstract] [Full Text]
*Margeta-Mitrovic M, Jan YN, Jan LY: Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors. Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14649-54. [Abstract] [Full Text]
*Kniazeff J, Galvez T, Labesse G, Pin JP: No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits. J Neurosci. 2002 Sep 1;22(17):7352-61. [Abstract] [Full Text]
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