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Rabbit Polyclonal to Mycobacterium tuberculosis antigen CFP10 (Rv3874)

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  11-490-C025 purified 0.025 mg yes choose region PDF datasheetHTML datasheet buy
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Background

The Mycobacterium tuberculosis antigen CFP10 (10 kDa culture filtrate antigen EsxB; LHP), also known as Rv3874, plays important role in mycobacterial virulence. It forms a complex with EsaT-6 protein.

Specificity

The rabbit polyclonal antibody to CFP10 recognizes the CFP10 (Rv3874) protein of Mycobacterium tuberculosis and Mycobacterium bovis.

Regulatory Status

Immunogen

CFP10 (Rv3874) of Mycobacterium tuberculosis

Species Reactivity:

  • Mycobacterium tuberculosis

Negative Species:

Applications:

  • Western Blotting
    Recommended dilution: 0.2 - 1 μg/ml
    Application note: Reducing conditions.
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

General references

  • *Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE 3rd, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream MA, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Squares S, Sulston JE, Taylor K, Whitehead S, Barrell BG.: Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature. 1998 Jun 11;393(6685):537-44. Erratum in: Nature 1998 Nov 12;396(6707):190. [Abstract]
  • *Arlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A: Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ). J Immunol. 2012 May 15;188(10):5020-31. [Abstract] [Full Text]
  • *Yang H, Chen H, Liu Z, Ma H, Qin L, Jin R, Zheng R, Feng Y, Cui Z, Wang J, Liu J, Hu Z: A novel B-cell epitope identified within Mycobacterium tuberculosis CFP10/ESAT-6 protein. PLoS One. 2013;8(1):e52848. [Abstract]
  • For research use only. Not for drug, diagnostic or other use.

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    Unless indicated otherwise, all products are For Research Use Only and not for diagnostic or therapeutic use. Not for resale or transfer either as a stand-alone product or as a component of another product without written consent of EXBIO. EXBIO will not be held responsible for patent infringement or other violations that may occur with the use of our products. All orders are accepted subject to EXBIO´s term and conditions which are available at www.exbio.cz.
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