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Mouse Monoclonal to CD10 / CALLA

LT10 (IgG1)

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  11-413-C025 purified 0.025 mg yes choose region PDF datasheetHTML datasheet buy
  11-413-C100 purified 0.1 mg yes choose region PDF datasheetHTML datasheet buy
  1F-413-T025 FITC 25 tests yes choose region PDF datasheetHTML datasheet buy
  1F-413-T100 FITC 100 tests yes choose region PDF datasheetHTML datasheet buy
  1P-413-T025 PE 25 tests yes choose region PDF datasheetHTML datasheet buy
  1P-413-T100 PE 100 tests yes choose region PDF datasheetHTML datasheet buy
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CD10 (neutral endopeptidase – NEP, common acute lymphocytic leukemia antigen – CALLA, membrane metallo-endopeptidase – MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.


The antibody LT10 reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.

Regulatory Status


mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation)

Species Reactivity:

  • Human
  • Other not tested

Negative Species:


  • Flow Cytometry
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

General references

  • *Suzuki T, Ino K, Kikkawa F, Uehara C, Kajiyama H, Shibata K, Mizutani S: Neutral endopeptidase/CD10 expression during phorbol ester-induced differentiation of choriocarcinoma cells through the protein kinase C- and extracellular signal-regulated kinase-dependent signalling pathway. Placenta. 2002 Jul;23(6):475-82. [Abstract]
  • *Yada K, Kashima K, Daa T, Kitano S, Fujiwara S, Yokoyama S: Expression of CD10 in basal cell carcinoma. Am J Dermatopathol. 2004 Dec;26(6):463-71. [Abstract]
  • *Braham H, Trimeche M, Ziadi S, Mestiri S, Mokni M, Amara K, Hachana M, Sriha B, Korbi S: CD10 expression by fusiform stromal cells in nasopharyngeal carcinoma correlates with tumor progression. Virchows Arch. 2006 Aug;449(2):220-4. [Abstract]
  • *Dall'Era MA, True LD, Siegel AF, Porter MP, Sherertz TM, Liu AY: Differential expression of CD10 in prostate cancer and its clinical implication. BMC Urol. 2007 Mar 2;7:3. [Abstract] [Full Text]
  • Product Specific References

  • *Leukocyte Typing VII., Mason D. et al. (Eds.), Oxford University Press (2002).
  • For research use only. Not for drug, diagnostic or other use.

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