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Mouse Monoclonal to HLA-G

MEM-G/4 (IgG1)

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  11-394-C025 purified 0.025 mg yes choose region PDF datasheetHTML datasheet buy
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Background

Specificity

The antibody MEM-G/4 reacts with denaturated HLA-G heavy chain. The recognized epitope is present only on HLA-G1, -G2 and -G5 molecules. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.

Regulatory Status

Immunogen

Recombinant human HLA-G denaturated heavy chain.

Species Reactivity:

  • Human

Negative Species:

Applications:

  • Western Blotting
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, Le Danff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N: Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules. Hum Immunol. 2003 Mar;64(3):315-26. [Abstract]
  • *Le Discorde M, Le Danff C, Moreau P, Rouas-Freiss N, Carosella ED: HLA-G*0105N null allele encodes functional HLA-G isoforms. Biol Reprod. 2005 Aug;73(2):280-8. [Abstract] [Full Text]
  • For research use only. Not for drug, diagnostic or other use.

    Related Products

  • Mouse IgG1 Isotype Control
  • Example Data

    MEM-G/4
    Fig. 1.


    Fig. 1. Western blotting analysis of HLA-G by the antibody MEM-G/4 on HLA-G1 transfectants (LCL-HLA-G1).

    Unless indicated otherwise, all products are For Research Use Only and not for diagnostic or therapeutic use. Not for resale or transfer either as a stand-alone product or as a component of another product without written consent of EXBIO. EXBIO will not be held responsible for patent infringement or other violations that may occur with the use of our products. All orders are accepted subject to EXBIOŽs term and conditions which are available at www.exbio.cz.
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