categories: MHC (Major Histocompatibility Complex) and Related Antigens (Human)

Mouse Monoclonal to HLA-G

MEM-G/4 (IgG1)

	Product No.	Form	Quantity	Stock	Price	Datasheet	Shop
	11-394-C025	purified	0.025 mg		choose region
	11-394-C100	purified	0.1 mg		choose region

- In stock! Ready for immediate despatch

- Manufacture on order

Background

Entrez Gene: 6p21.3

Specificity

The antibody MEM-G/4 reacts with denaturated HLA-G heavy chain. The recognized epitope is present only on HLA-G1, -G2 and -G5 molecules. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.

Immunogen

Recombinant human HLA-G denaturated heavy chain.

Species Reactivity: Human Negative Species:	Applications: Western Blotting Usage note: Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.	Product Specific References Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, Le Danff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N: Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules. Hum Immunol. 2003 Mar;64(3):315-26. [Abstract] Le Discorde M, Le Danff C, Moreau P, Rouas-Freiss N, Carosella ED: HLA-G*0105N null allele encodes functional HLA-G isoforms. Biol Reprod. 2005 Aug;73(2):280-8. [Abstract] [Full Text]

Species Reactivity:

Human

Negative Species:

Applications:

Western Blotting

Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

*Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, Le Danff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N: Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules. Hum Immunol. 2003 Mar;64(3):315-26. [Abstract]

*Le Discorde M, Le Danff C, Moreau P, Rouas-Freiss N, Carosella ED: HLA-G*0105N null allele encodes functional HLA-G isoforms. Biol Reprod. 2005 Aug;73(2):280-8. [Abstract] [Full Text]

For research use only. Not for drug, diagnostic or other use.

Related Products

Mouse IgG1 Isotype Control

Example Data

Fig. 1.

Fig. 1. Western blotting analysis of HLA-G by the antibody MEM-G/4 on HLA-G1 transfectants (LCL-HLA-G1).

PRODUCTS