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Mouse Monoclonal to HLA-G

MEM-G/11 (IgG1)

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Product No. Form Quantity Stock Price Datasheet Shop
  11-389-C025 purified 0.025 mg yes choose region PDF datasheetHTML datasheet buy
  11-389-C100 purified 0.1 mg yes choose region PDF datasheetHTML datasheet buy
  1F-389-C025 FITC 0.025 mg yes choose region PDF datasheetHTML datasheet buy
  1F-389-C100 FITC 0.1 mg yes choose region PDF datasheetHTML datasheet buy
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Background

Specificity

The antibody MEM-G/11 recognizes HLA-G1 antigen. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.

Regulatory Status

Immunogen

Recombinant human HLA-G refolded with beta2-microglobulin and peptide.

Species Reactivity:

  • Human

Negative Species:

Applications:

  • Immunoprecipitation
  • Flow Cytometry
    The antibody MEM-G/11 does not cross-block standard MEM-G/9 antibody.
    Recommended dilution:2 μg/ml
  • Immunohistochemistry (frozen sections)
  • ELISA
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

General references

  • *Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, Le Danff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N: Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules. Hum Immunol. 2003 Mar;64(3):315-26. [Abstract]
  • Product Specific References

  • *Boyson JE, Erskine R, Whitman MC, Chiu M, Lau JM, Koopman LA, Valter MM, Angelisova P, Horejsi V, Strominger JL.: Disulfide bond-mediated dimerization of HLA-G on the cell surface. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16180-5. [Abstract] [Full Text]
  • For research use only. Not for drug, diagnostic or other use.

    Related Products

  • Mouse IgG1 Isotype Control
  • Example Data


    MEM-G/11
    Fig. 1. Flow Cytometry analysis


    Fig. 1. Surface staining of JEG-3 human choriocarcinoma cell line with anti-human HLA-G (MEM-G/11) FITC.
    Total viable cells were used for analysis.

    Unless indicated otherwise, all products are For Research Use Only and not for diagnostic or therapeutic use. Not for resale or transfer either as a stand-alone product or as a component of another product without written consent of EXBIO. EXBIO will not be held responsible for patent infringement or other violations that may occur with the use of our products. All orders are accepted subject to EXBIO´s term and conditions which are available at www.exbio.cz.
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