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Mouse Monoclonal to TCR beta (Vbeta5.3-related)

MEM-262 (IgG2a)

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Specificity

The antibody MEM-262 recognizes beta chains of the TCR expressed by HPB-ALL cell line [carrying V(beta5.3)] and a small subset of peripheral blood T cells. This subset is larger than that recognized by other V(beta5.3)-specific antibodies.

Regulatory Status

Immunogen

Human thymoma cell line HPB-ALL.

Species Reactivity:

  • Human
  • Other not tested

Negative Species:

Applications:

  • Flow Cytometry
  • Immunoprecipitation
  • Western Blotting
    Uniquely recognizes denatured TCR beta chains under the conditions of Western blotting.
  • Functional Application
    Activates T cells (V beta 5-related subset)
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *Pavlistova D, Drbal K, Hilgert I, Horejsi V: A novel monoclonal reagent recognizing native and denatured Vbeta5.3-related chains of human T cell receptor. Immunol Lett. 2003 Aug 5;88(2):105-8. [Abstract]
  • For research use only. Not for drug, diagnostic or other use.

    Example Data

    Unless indicated otherwise, all products are For Research Use Only and not for diagnostic or therapeutic use. Not for resale or transfer either as a stand-alone product or as a component of another product without written consent of EXBIO. EXBIO will not be held responsible for patent infringement or other violations that may occur with the use of our products. All orders are accepted subject to EXBIO´s term and conditions which are available at www.exbio.cz.
    © 2003 EXBIO. All rights reserved.
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