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Mouse Monoclonal to HSV2 (gG)

T303 (IgG2a)

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Background

Herpes Simplex Virus (HSV) is a virus that manifests itself in two common viral infections. There are actually two types of Herpes Simplex Virus, HSV1 and HSV2. These are very similar in many ways, and both can cause either oral herpes or genital herpes. HSV1 - most commonly develops into Oral Herpes infecting the lips (fever blisters or cold sores). HSV1 can also infect the genital area causing sores to develop. HSV2 - generally infects the genital area (Genital Herpes); however, HSV2 can also infect the mouth.

Specificity

The antibody T303 recognizes gG antigen of HSV2 (Herpes Simplex Virus type 2), a dsDNA virus, member of Herpesviridae family.

Regulatory Status

Immunogen

Exctract of HSV-2 infected VERO (green monkey kidney) cells.

Species Reactivity:

  • HSV

Negative Species:

Applications:

  • Western Blotting
  • Immunocytochemistry
  • ELISA
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *Bystricka M, Vancikova M, Kasalova M, Rajcani J, Kostal M, Muranyiova M, Polakova K, Russ G: Type-common and type-specific monoclonal antibodies to herpes simplex virus types 1 and 2. Acta Virol. 1991 Apr;35(2):152-64. [Abstract]
  • *Bystricka M, Petrikova M, Zatovicova M, Solarikova L, Kostolansky F, Mucha V, Russ G: Monoclonal antibodies to the distinct antigenic sites on glycoproteins C and B and their protective abilities in herpes simplex virus infection. Acta Virol. 1997 Feb;41(1):5-12. [Abstract]
  • *Bystricka M, Solarikova L, Gasparikova L, Stanekova D, Mokras M, Kovacova E, Sabo A, Russ G: Antibody responses to the herpes simplex virus type 2 glycoprotein G in sera of human immunodeficiency virus-infected patients in Slovakia. Acta Virol. 1998 Nov;42(5):319-24. [Abstract]
  • *Bystricka M, Zatovicova M, Petrikova M, Solarikova L, Russ G, Ziegler T: Monoclonal antibodies suitable for type-specific identification of herpes simplex viruses by a rapid culture assay. Acta Virol. 1999 Dec;43(6):399-402. [Abstract]
  • For research use only. Not for drug, diagnostic or other use.

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