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Mouse Monoclonal to HSV1 + HSV2 (gB)

T111 (IgG2b)

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Background

Herpes Simplex Virus (HSV) is a virus that manifests itself in two common viral infections. There are actually two types of Herpes Simplex Virus, HSV1 and HSV2. These are very similar in many ways, and both can cause either oral herpes or genital herpes. HSV1 - most commonly develops into Oral Herpes infecting the lips (fever blisters or cold sores). HSV1 can also infect the genital area causing sores to develop. HSV2 - generally infects the genital area (Genital Herpes); however, HSV2 can also infect the mouth.

Specificity

The antibody T111 recognizes gB antigen of both HSV1 and HSV2 (Herpes Simplex Virus type 1 and 2), a dsDNA virus, member of Herpesviridae family.

Regulatory Status

Immunogen

Exctract of HSV-1 infected VERO (green monkey kidney) cells.

Species Reactivity:

  • HSV

Negative Species:

Applications:

  • Immunocytochemistry
  • ELISA
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *Bystricka M, Vancikova M, Kasalova M, Rajcani J, Kostal M, Muranyiova M, Polakova K, Russ G: Type-common and type-specific monoclonal antibodies to herpes simplex virus types 1 and 2. Acta Virol. 1991 Apr;35(2):152-64. [Abstract]
  • *Bystricka M, Petrikova M, Zatovicova M, Solarikova L, Kostolansky F, Mucha V, Russ G: Monoclonal antibodies to the distinct antigenic sites on glycoproteins C and B and their protective abilities in herpes simplex virus infection. Acta Virol. 1997 Feb;41(1):5-12. [Abstract]
  • *Bystricka M, Zatovicova M, Petrikova M, Solarikova L, Russ G, Ziegler T: Monoclonal antibodies suitable for type-specific identification of herpes simplex viruses by a rapid culture assay. Acta Virol. 1999 Dec;43(6):399-402. [Abstract]
  • For research use only. Not for drug, diagnostic or other use.

    Related Products

  • Mouse IgG2b Isotype Control
  • Example Data

    T111
    Fig. 1.

    Detection of HSV by monoclonal antibody T111 in infected cells.

    Unless indicated otherwise, all products are For Research Use Only and not for diagnostic or therapeutic use. Not for resale or transfer either as a stand-alone product or as a component of another product without written consent of EXBIO. EXBIO will not be held responsible for patent infringement or other violations that may occur with the use of our products. All orders are accepted subject to EXBIO´s term and conditions which are available at www.exbio.cz.
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