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by categories | a-z list | Application type: Flow Cytometry | Immunohistochemistry | Functional Studies
categories: Hormones (Human)

Mouse Monoclonal to Thyrotropin (hTSH)

TSH-116 (IgG2a)

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Background

Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha nad beta.

Specificity

The antibody TSH-116 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain.
The TSH-116 reacts with association constant 1.1 x 1011 l/mol.
Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-116: hTSH (78.9), hCG (20.3), hLH (23.2), hFSH (29.9).

Regulatory Status

Immunogen

Human thyrotropin.

Species Reactivity:

  • Human

Negative Species:

Applications:

  • ELISA
  • RIA
    The antibody TSH-116 is suitable in combination with the antibody TSH-51 for immunometric assays in the screening of neonatal hypothyroidism.
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *Jirkalova V, Cap J, Strakova H, Pribysova J, Plicka J, Lomsky R: Immunoradiometric and luminescence immunoenzymometric assay of human thyrotropin from dried blood spots for screening of neonatal hypothyroidism. Eur J Clin Chem Clin Biochem. 1996 Oct;34(10):823-7. [Abstract]
  • For research use only. Not for drug, diagnostic or other use.

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  • Mouse IgG2a Isotype Control
  • Example Data

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