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by categories | a-z list | Application type: Flow Cytometry | Immunohistochemistry | Functional Studies
categories: Hormones (Human)

Mouse Monoclonal to C-peptide

C-PEP-01 (IgG1)

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  11-247-C025 purified 0.025 mg yes choose region PDF datasheetHTML datasheet buy
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Background

From every molecule of Proinsulin, one molecule of Insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to Insulin.

Specificity

The antibody C-PEP-01 reacts specifically with C-peptide, a part of the Proinsulin molecule. Proinsulin consists of the three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the Insulin molecule).
No cross-reactivity with Insulin or other peptide hormones or proteins was observed.

Regulatory Status

Immunogen

Human C-peptide conjugated to bovine serum albumin.

Species Reactivity:

  • Human

Negative Species:

Applications:

  • ELISA
  • RIA
  • Immunohistochemistry (paraffin sections)
    Recommended dilution:
    purified 2-5 μg/ml
    biotin 25 μg/ml
    Positive control:
    human pancreas (islets of Langerhans)
  • Immunocytochemistry
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *Hilgert I, Stolba P, Kristofova H, Stefanova I, Bendlova B, Lebl M, Horejsi V: A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA. Hybridoma. 1991 Jun;10(3):379-86. [Abstract]
  • For research use only. Not for drug, diagnostic or other use.

    Related Products

  • Mouse IgG1 Isotype Control
  • Example Data


    C-PEP-01
    Fig. 1. Immunohistochemistry of paraffin-embedded sections (human pancreas)




    Fig. 1. Immunohistochemistry staining of human pancreas (paraffin-embedded sections) with anti-human to C-peptide of Proinsulin (C-PEP-01).

    Unless indicated otherwise, all products are For Research Use Only and not for diagnostic or therapeutic use. Not for resale or transfer either as a stand-alone product or as a component of another product without written consent of EXBIO. EXBIO will not be held responsible for patent infringement or other violations that may occur with the use of our products. All orders are accepted subject to EXBIO´s term and conditions which are available at www.exbio.cz.
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