Mouse Monoclonal to C-peptide of Proinsulin
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From every molecule of Proinsulin, one molecule of Insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to Insulin.
The antibody C-PEP-01 reacts specifically with C-peptide, a part of the Proinsulin molecule. Proinsulin consists of the three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the Insulin molecule).
No cross-reactivity with Insulin or other peptide hormones or proteins was observed.
Human C-peptide conjugated to bovine serum albumin.
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.
Product Specific References
*Hilgert I, Stolba P, Kristofova H, Stefanova I, Bendlova B, Lebl M, Horejsi V: A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA.
Hybridoma. 1991 Jun;10(3):379-86.
For research use only. Not for drug, diagnostic or other use.
Mouse IgG1 Isotype Control
Fig. 1. Immunohistochemistry of paraffin-embedded sections (human pancreas)
Immunohistochemistry staining of human pancreas (paraffin-embedded sections) with anti-human to C-peptide of Proinsulin (C-PEP-01