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Mouse Monoclonal to Prostate-specific antigen (PSA)

A67-B/E3 (IgG1)

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Background

Prostate-specific antigen (PSA) is a protein produced by normal prostate cells. This enzyme participates in the dissolution of the seminal fluid coagulum and plays an important role in fertility. The highest amounts of PSA are found in the seminal fluid; some PSA escapes the prostate and can be found in the serum. This serum component has been used to track the response to therapy in men with prostate cancer.
ISOBM TD-3 PSA Workshop code: 207

Specificity

The antibody A67-B/E3 reacts with prostate-specific antigen (PSA),a protein produced by normal prostate cells. The highest amounts of PSA are found in the seminal fluid.

Regulatory Status

Immunogen

30 KDa protein fraction prepared from human seminal plasma

Species Reactivity:

  • Human

Negative Species:

Applications:

  • Immunohistochemistry (paraffin sections)
  • Western Blotting
    Positive material: seminal plasma
  • ELISA
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *Rye P.D. et al. (Eds.): Summary Report on the ISOBM TD-3 Workshop, Tum. Biol. 20 (S1), pp 1-94 (1999).
  • For research use only. Not for drug, diagnostic or other use.

    Related Products

  • Mouse IgG1 Isotype Control
  • Native human Prostate-specific antigen / PSA
  • Example Data


    A67-B/E3
    Fig. 1. Immunohistochemistry of paraffin sections (prostate)



    Fig. 1. Immunohistochemistry staining of prostate (paraffin-embedded sections) with anti-human Prostate-specific antigen (A67-B/E3).

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