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Mouse Monoclonal to IgA secretory component

SC-05 (IgG1)

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  11-112-C025 purified 0.025 mg yes choose region PDF datasheetHTML datasheet buy
  11-112-C100 purified 0.1 mg yes choose region PDF datasheetHTML datasheet buy
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Specificity

The antibody SC-05 reacts with 80 kDa human secretory component glycoprotein (both free and bound in secretory IgA). Recognized glycoprotein is specific membrane marker of glandular carcinomas.

Regulatory Status

Immunogen

Affinity-purified secretory component from human colostrum.

Species Reactivity:

  • Human

Negative Species:

Applications:

  • Immunoprecipitation
  • Western Blotting
  • Immunohistochemistry (paraffin sections)
  • Immunohistochemistry (frozen sections)
    examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland.
Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

  • *Kvale D, Bartek J, Sollid LM, Brandtzaeg P: Rapid selection of cultured cells with increased expression of a membrane marker (secretory component). Int J Cancer. 1988 Oct 15;42(4):638-41. [Abstract]
  • *Bartek J, Tlaskalova-Hogenova H, Staskova Z, Simeckova J, Vojtesek B, Rejthar A, Kovarik J, Bartkova J: Secretory component in differentiating normal epithelium, benign lesions and malignancy in the human breast as monitored by monoclonal antibodies. Histochemistry. 1989;91(3):235-44. [Abstract]
  • *Bartek J, Bartkova J, Taylor-Papadimitriou J: Keratin 19 expression in the adult and developing human mammary gland. Histochem J. 1990 Oct;22(10):537-44. [Abstract]
  • For research use only. Not for drug, diagnostic or other use.

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