Mouse Monoclonal to Benzo[a]pyrene

BAP-13 (IgG1)

	Product No.	Form	Quantity	Stock	Price	Datasheet	Shop
	11-339-C025	purified	0.025 mg		choose region
	11-339-C100	purified	0.1 mg		choose region

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Specificity

The antibody BAP-13 is specific for Polynuclear Aromatic Hydrocarbons.
The antibody BAP-13 inhibits DNA adduct formation (this ability was investigated in rat liver microsomes spiked with calf thymus DNA and 7,8-diol-B[a]P).

Immunogen

Benzo[a]pyrenyl-1-butyric acid conjugated to BSA.

Species Reactivity: Negative Species:	Applications: Immunocytochemistry The antibody BAP-13 is suitable for immunocytochemical analysis of DNA and protein adducts of benzo[a]pyrene in tissues of various species. ELISA Usage note: Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.	Product Specific References Suchanek M, Scharnweber T, Fisher M, Knopp D, Niessner R: Monoclonal antibodies specific to polynuclear aromatic hydrocarbons. Folia Biol (Praha). 2001;47(3):106-7. Scharnweber T, Fisher M, Suchanek M, Knopp D, Niessner R: Monoclonal antibody to polycyclic aromatic hydrocarbons based on a new benzo[a]pyrene immunogen. Fresenius J Anal Chem. 2001 Nov;371(5):578-85. [Abstract] *De Buck SS, Bouche FB, Brandenburger A, Muller CP: Modulation of the metabolism and adverse effects of benzo[a]pyrene by a specific antibody: a novel host factor in environmental carcinogenesis? Carcinogenesis. 2005 Apr;26(4):835-44. [Abstract] [Full Text]

Species Reactivity:

Negative Species:

Applications:

Immunocytochemistry
The antibody BAP-13 is suitable for immunocytochemical analysis of DNA and protein adducts of benzo[a]pyrene in tissues of various species.
ELISA

Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Product Specific References

*Suchanek M, Scharnweber T, Fisher M, Knopp D, Niessner R: Monoclonal antibodies specific to polynuclear aromatic hydrocarbons. Folia Biol (Praha). 2001;47(3):106-7.

*Scharnweber T, Fisher M, Suchanek M, Knopp D, Niessner R: Monoclonal antibody to polycyclic aromatic hydrocarbons based on a new benzo[a]pyrene immunogen. Fresenius J Anal Chem. 2001 Nov;371(5):578-85. [Abstract]

*De Buck SS, Bouche FB, Brandenburger A, Muller CP: Modulation of the metabolism and adverse effects of benzo[a]pyrene by a specific antibody: a novel host factor in environmental carcinogenesis? Carcinogenesis. 2005 Apr;26(4):835-44. [Abstract] [Full Text]

For research use only. Not for drug, diagnostic or other use.

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